Phylogeography, Transmission, and Viral Proteins of Nipah Virus
نویسندگان
چکیده
منابع مشابه
Foodborne Transmission of Nipah Virus, Bangladesh
We investigated an outbreak of encephalitis in Tangail District, Bangladesh. We defined case-patients as persons from the outbreak area in whom fever developed with new onset of seizures or altered mental status from December 15, 2004, through January 31, 2005. Twelve persons met the definition; 11 (92%) died. Serum specimens were available from 3; 2 had immunoglobulin M antibodies against Nipa...
متن کاملNipah Virus Transmission in a Hamster Model
Based on epidemiological data, it is believed that human-to-human transmission plays an important role in Nipah virus outbreaks. No experimental data are currently available on the potential routes of human-to-human transmission of Nipah virus. In a first dose-finding experiment in Syrian hamsters, it was shown that Nipah virus was predominantly shed via the respiratory tract within nasal and o...
متن کاملSerum from Nipah Virus Patients Recognises Recombinant Viral Proteins Produced in Escherichia coli.
The genes for Nipah virus (NiV) proteins were amplified from viral RNA, cloned into the plasmid pTriEx-3 Hygro, expressed, and purified using immobilized metal affinity chromatography. The recombinant N, F, and G NiV proteins (rNiV-N, rNiV-F, and rNiV-G), were successfully expressed in Escherichia coli and purified with a yield of 4, 16, and 4 mg/L, respectively. All 3 recombinant viral protein...
متن کاملTransmission Routes for Nipah Virus from Malaysia and Bangladesh
Human infections with Nipah virus in Malaysia and Bangladesh are associated with markedly different patterns of transmission and pathogenicity. To compare the 2 strains, we conducted an in vivo study in which 2 groups of ferrets were oronasally exposed to either the Malaysia or Bangladesh strain of Nipah virus. Viral shedding and tissue tropism were compared between the 2 groups. Over the cours...
متن کاملFeral Cats and Risk for Nipah Virus Transmission
To the Editor: Nipah virus (NiV) emerged in peninsular Malaysia in 1998 and 1999 as a respiratory and neurologic disease of domestic pigs and an acute febrile encephalitic disease in humans (1). Nipah virus infection is associated with a case-fatality ratio of 40% to 76% in humans (1,2). Cats (Felis catus) were infected with NiV at the site of the outbreak in northern Malaysia (3). Experimental...
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ژورنال
عنوان ژورنال: Virologica Sinica
سال: 2018
ISSN: 1674-0769,1995-820X
DOI: 10.1007/s12250-018-0050-1